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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP9A All Species: 32.73
Human Site: Y495 Identified Species: 60
UniProt: O75110 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75110 NP_006036.1 1047 118583 Y495 Y E D S C R V Y Q A S S P D E
Chimpanzee Pan troglodytes XP_514727 875 98509 D348 G L T L V G R D Q S S M Q L R
Rhesus Macaque Macaca mulatta XP_001098852 1044 118009 Y492 Y E D S C R V Y Q A S S P D E
Dog Lupus familis XP_534457 1043 118292 Y491 Y E D S C R V Y Q A S S P D E
Cat Felis silvestris
Mouse Mus musculus O70228 1047 118590 Y495 F E D S C R V Y Q A S S P D E
Rat Rattus norvegicus XP_002726328 995 111897 A468 C N G V T D Q A E A E K Q F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509092 1116 127035 Y564 Y E D T C R V Y Q A S S P D E
Chicken Gallus gallus XP_417508 1115 125396 Y563 Y E D S C R V Y Q A S S P D E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038619 1108 125101 Y556 F S D D N R T Y Q A S S P D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396589 1276 146194 Y725 V P E Q K R N Y Q A S S P D E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799223 1105 125600 Y553 D Q E A S I V Y Q A S S P D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98205 1107 124818 L480 F V G K N A N L L E I R F N G
Baker's Yeast Sacchar. cerevisiae P40527 1151 130199 L609 K F T E S V G L S L F K R D R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 97.8 97.4 N.A. 97.9 89.7 N.A. 90.2 89.5 N.A. 71.3 N.A. N.A. 54.3 N.A. 60.4
Protein Similarity: 100 83.5 98.2 98.2 N.A. 99.5 91.8 N.A. 92.2 91.5 N.A. 82.4 N.A. N.A. 66.8 N.A. 74.4
P-Site Identity: 100 13.3 100 100 N.A. 93.3 13.3 N.A. 93.3 100 N.A. 66.6 N.A. N.A. 60 N.A. 60
P-Site Similarity: 100 20 100 100 N.A. 100 20 N.A. 100 100 N.A. 73.3 N.A. N.A. 66.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 29 44.6 N.A.
Protein Similarity: N.A. N.A. N.A. 48.4 62.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 8 0 77 0 0 0 0 0 % A
% Cys: 8 0 0 0 47 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 54 8 0 8 0 8 0 0 0 0 0 77 0 % D
% Glu: 0 47 16 8 0 0 0 0 8 8 8 0 0 0 77 % E
% Phe: 24 8 0 0 0 0 0 0 0 0 8 0 8 8 0 % F
% Gly: 8 0 16 0 0 8 8 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 0 0 8 8 0 0 0 0 0 0 16 0 0 0 % K
% Leu: 0 8 0 8 0 0 0 16 8 8 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 0 16 0 16 0 0 0 0 0 0 8 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 70 0 0 % P
% Gln: 0 8 0 8 0 0 8 0 77 0 0 0 16 0 0 % Q
% Arg: 0 0 0 0 0 62 8 0 0 0 0 8 8 0 16 % R
% Ser: 0 8 0 39 16 0 0 0 8 8 77 70 0 0 0 % S
% Thr: 0 0 16 8 8 0 8 0 0 0 0 0 0 0 0 % T
% Val: 8 8 0 8 8 8 54 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 39 0 0 0 0 0 0 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _